Osamu Onodera Selected Research

Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)

11/2020	TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons.
1/2016	Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes.
8/2012	Primary lateral sclerosis: upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration--immunohistochemical and biochemical analyses of TDP-43.
11/2010	[FTLD/ALS as TDP-43 proteinopathies].
7/2010	Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity.
10/2009	Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.
8/2008	Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions.
4/2008	TDP-43 mutation in familial amyotrophic lateral sclerosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Osamu Onodera Research Topics

Disease

21	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 02/2007
15	Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy 04/2023 - 04/2009
11	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 05/2004
9	Ataxia (Dyssynergia) 05/2023 - 03/2005
8	Cerebral Small Vessel Diseases 11/2023 - 04/2009
8	Stroke (Strokes) 11/2023 - 05/2016
8	Ischemic Stroke 11/2023 - 01/2017
8	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 11/2020 - 04/2008
7	Dementia (Dementias) 04/2015 - 03/2005
5	Parkinson Disease (Parkinson's Disease) 01/2023 - 04/2008
5	Motor Neuron Disease (Primary Lateral Sclerosis) 07/2021 - 10/2009
5	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2020 - 03/2004
4	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 09/2023 - 05/2002
4	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 11/2007
4	Early-onset ataxia with oculomotor apraxia and hypoalbuminemia 01/2021 - 01/2009
4	Cognitive Dysfunction 03/2019 - 01/2016
3	Disease Progression 01/2022 - 11/2011
3	Hypertension (High Blood Pressure) 12/2020 - 11/2011
3	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 10/2020 - 04/2007
3	Brain Ischemia (Cerebral Ischemia) 10/2020 - 01/2017
3	Huntington Disease (Huntington's Disease) 01/2020 - 03/2004
3	Atrophy 10/2019 - 02/2009
2	Optic Neuritis (Retrobulbar Neuritis) 04/2024 - 09/2021
2	Headache (Headaches) 10/2023 - 07/2017
2	Muscle Weakness 06/2023 - 01/2018
2	Multiple System Atrophy 05/2023 - 01/2022
2	Hypoxia (Hypoxemia) 01/2023 - 06/2007
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 08/2010
2	Sarcoma (Soft Tissue Sarcoma) 01/2023 - 01/2016
2	Leukoencephalopathies 01/2023 - 01/2007
2	Amyloidosis 05/2022 - 11/2005
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 02/2022 - 03/2019
2	Corticobasal Degeneration 01/2022 - 07/2010
2	CADASIL 08/2021 - 03/2013
2	Cerebellar Ataxia (Dysmetria) 12/2020 - 01/2020
2	Infections 11/2020 - 07/2003
2	X-Linked Bulbo-Spinal Atrophy 01/2020 - 10/2009
2	Brain Diseases (Brain Disorder) 01/2020 - 02/2009
2	Spinocerebellar Degenerations (Marinesco Sjogren Syndrome) 01/2020 - 04/2007
2	Apraxias (Dyspraxia) 01/2010 - 03/2007
2	autosomal recessive 1 Spinocerebellar ataxia 11/2009 - 01/2009
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 03/2005 - 01/2003
1	Autoimmune Diseases (Autoimmune Disease) 04/2024
1	Transverse Myelitis (Necrotizing Myelitis) 04/2024
1	Neuromyelitis Optica (Devic's Disease) 04/2024
1	Demyelinating Diseases (Demyelinating Disease) 04/2024
1	Autoimmune Diseases of the Nervous System 04/2024
1	Respiratory Insufficiency (Respiratory Failure) 04/2024
1	Acquired CJD 12/2023
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 12/2023
1	Fatal Familial Insomnia 12/2023
1	Type 2 Diabetes Mellitus (MODY) 11/2023
1	X-Linked Torsion Dystonia 3 09/2023
1	Dystonia (Limb Dystonia) 09/2023
1	Familial paroxysmal dystonia 09/2023
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 09/2023
1	Woodhouse Sakati syndrome 09/2023

Drug/Important Bio-Agent (IBA)

18	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2023 - 05/2007
14	Proteins (Proteins, Gene)FDA Link 11/2021 - 01/2003
9	polyglutamineIBA 10/2020 - 05/2002
8	Peptide Hydrolases (Proteases)FDA Link 04/2023 - 06/2010
6	Serine (L-Serine)FDA Link 04/2023 - 06/2010
6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 03/2004
5	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2017
5	Oxygen (Dioxygen)IBA 01/2023 - 06/2007
5	High-Temperature Requirement A Serine Peptidase 1IBA 11/2021 - 01/2017
5	UbiquitinIBA 01/2017 - 02/2007
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 10/2008
4	alpha-SynucleinIBA 06/2010 - 04/2007
3	Nuclear Proteins (Protein, Nuclear)IBA 09/2022 - 08/2008
3	SteroidsIBA 05/2020 - 07/2003
3	Amyloid (Amyloid Fibrils)IBA 03/2020 - 01/2008
3	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2019 - 01/2017
3	ORALIT (ORS)IBA 03/2019 - 01/2016
3	Retinaldehyde (Retinal)IBA 03/2013 - 03/2005
3	Transforming Growth Factor beta (TGF-beta)IBA 08/2011 - 04/2009
3	Presenilin-1IBA 01/2008 - 03/2005
2	AntibodiesIBA 04/2024 - 04/2024
2	PrionsIBA 12/2023 - 01/2013
2	EnzymesIBA 05/2023 - 11/2020
2	SynucleinsIBA 01/2023 - 01/2022
2	Macrophage Colony-Stimulating FactorIBA 01/2023 - 01/2014
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2010
2	Arginine (L-Arginine)FDA Link 01/2020 - 01/2017
2	U12 small nuclear RNAIBA 02/2014 - 10/2013
2	RNA (Ribonucleic Acid)IBA 01/2014 - 08/2006
2	Fibronectins (Fibronectin)IBA 05/2011 - 06/2010
2	AldehydesIBA 11/2009 - 01/2009
1	Aquaporins (Water Channels)IBA 04/2024
1	AutoantibodiesIBA 04/2024
1	Methylprednisolone FDA LinkGeneric 04/2024
1	Prion ProteinsIBA 12/2023
1	Neuroprotective AgentsIBA 11/2023
1	Metformin (Glucophage)FDA LinkGeneric 11/2023
1	Hypoglycemic Agents (Hypoglycemics)IBA 11/2023
1	Verapamil (Calan)FDA LinkGeneric 10/2023

Therapy/Procedure

17	Therapeutics 04/2024 - 07/2003
3	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2023 - 01/2017
2	Stem Cell Transplantation 02/2022 - 03/2019
2	Tracheostomy 01/2022 - 11/2018